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Search Results for " Vascular endothelial growth factor receptor "

ターゲット

143

阻害剤

15

天然化合物

80

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T5466 Tyrosine kinase-IN-1 VEGFR , FGFR , FLT , PDGFR
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively)
T9724 VEGFR2-IN-2 Others
VEGFR2-IN-2 has anti-inflammatory and analgesic activities.
T6996 SU 5402 SU5402 VEGFR , FGFR , PDGFR
SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
T2642 PD173074 Apoptosis , EGFR , VEGFR , FGFR , IGF-1R , Src
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
T12598 Pz-1 VEGFR , c-RET
T16975 TAK-593 VEGFR , PDGFR
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).
T5475 ZD-4190 EGFR , VEGFR
ZD-4190 is a compound that inhibits both the vascular endothelial growth factor receptor 2 (VEGFR2) and the epidermal growth factor receptor (EGFR) signaling pathways, utilized in cancer treatment.
TQ0321 BIBF 1202 VEGFR
BIBF 1202 is a VEGFR2 kinase inhibitor (IC50: 62 nM).
T2446 KI8751 EGFR , VEGFR , FGFR , PDGFR , c-Kit
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
T9979 VEGFR-2-IN-29 VEGFR
VEGFR-2-IN-29 is a VEGFR2 inhibitor.
T7945 SU14813 VEGFR , PDGFR , c-Kit
SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).
TQ0041 Ningetinib Tosylate VEGFR , c-Met/HGFR , TAM Receptor
Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
T6012 SAR131675 SAR 131675 VEGFR
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.
T15185 Lucitanib E-3810 VEGFR , FGFR
Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively).
T1777 Nintedanib BIBF 1120,Intedanib VEGFR , FGFR , FLT , PDGFR , Src
Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...
T3566 SU5205 SU 5205 VEGFR
SU5205 is a VEGFR2 inhibitor.
T2419 BMS-794833 VEGFR , c-Met/HGFR
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.
T9929 Ramucirumab VEGFR
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T2415 PP121 Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).
T7611 ODM-203 VEGFR , FGFR
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
T0097L Pazopanib GW786034 VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...
T6166 Telatinib Bay 57-9352 VEGFR , PDGFR , c-Kit
Telatinib (Bay 57-9352) is an effective inhibitor of VEGFR2/3, c-Kit, and PDGFRα. The IC50s of Telatinib forVEGFR2/3, c-Kit and PDGFRα are 6 nM/4 nM, 1 nM, and 15 nM, respectively.
TQ0317 R1530 R-1530,R 1530 VEGFR , FGFR , FLT , PDGFR
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
T11520 GW806742X MLK , VEGFR
GW806742X is an inhibitor of Mixed Lineage Kinase Domain-Like protein (MLKL) which binds the MLKL pseudokinase domain (Kd: 9.3 μM) with anti-necroptosis activity. GW806742X has activity against VEGFR2.
T0520 Lenvatinib E7080 VEGFR , FGFR , c-RET , PDGFR , c-Kit
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (...
T3476 JI-101 CGI-1842,JI 101 VEGFR , PDGFR , Ephrin Receptor
JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), platelet derived growth factor receptor β (PDGFR-β), and ephrin type-B receptor 4 (EphB4).
T2358 ENMD-2076 Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T3570 SU4312 SU 4312,NSC 86429 VEGFR , PDGFR
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotox...
T1452 Axitinib AG-013736 VEGFR , PDGFR , c-Kit
Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.
T4288 HVEGF-IN-1 VEGFR
hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.
T2064 Semaxinib SU5416 VEGFR
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the...
T9928 Ranibizumab VEGFR
Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121, and VEGF165. Ranibizumab's ability to selectively target and n...
T4318 EOC317 ACTB-1003,ACTB1003,ACTB 1003 VEGFR , FGFR , Tie-2
EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).
T2638 Gandotinib LY2784544 VEGFR , FGFR , FLT , JAK
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.
T13178 Toceranib PHA 291639E,SU11654 VEGFR , PDGFR , c-Kit
T2500 Cediranib AZD2171,NSC-732208 VEGFR , FLT , PDGFR , c-Kit , Autophagy
Cediranib (AZD2171) (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit...
T2372 Ponatinib AP24534 VEGFR , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Autophagy
Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively).
T3691 (Rac)-SAR131675 SAR131675 VEGFR
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h...
T6036 Brivanib BMS-540215 EGFR , VEGFR , FGFR , Autophagy
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
T1656 Vandetanib ZD6474 Apoptosis , EGFR , VEGFR , Autophagy
Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.
T2656 Fruquintinib HMPL-013 VEGFR
Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.
T1836 AZD2932 VEGFR , FLT , PDGFR , c-Kit
AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.
T1792L Regorafenib monohydrate Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect...
T2032 WHI-P180 Janex 3 EGFR , VEGFR , c-RET , CDK
WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.
TQ0059 Ilorasertib ABT-348 VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...
T8402 Regorafenib Hydrochloride BAY73-4506 hydrochloride Raf , VEGFR , c-RET , PDGFR , Autophagy
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
T8541 Lenvatinib mesylate E7080 (mesylate) VEGFR , FGFR , c-RET , PDGFR , c-Kit
Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.
T6184 Orantinib SU6668,TSU-68,NSC 702827 Apoptosis , VEGFR , FGFR , PDGFR
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, A...
T21593 AAL-993 VEGFR
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogeni...

Compounds

Tyrosine kinase-IN-1
T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
VEGFR2-IN-2
T9724
Synonym:
Target: Others
SU 5402
T6996
Synonym: SU5402
Target: VEGFR, FGFR, PDGFR
JK-P3
T4425
Synonym:
Target: VEGFR
PD173074
T2642
Synonym:
Target: Apoptosis, EGFR, VEGFR, FGFR, IGF-1R, Src
Pz-1
T12598
Synonym:
Target: VEGFR, c-RET
TAK-593
T16975
Synonym:
Target: VEGFR, PDGFR
ZD-4190
T5475
Synonym:
Target: EGFR, VEGFR
BIBF 1202
TQ0321
Synonym:
Target: VEGFR
KI8751
T2446
Synonym:
Target: EGFR, VEGFR, FGFR, PDGFR, c-Kit
VEGFR-2-IN-29
T9979
Synonym:
Target: VEGFR
SU14813
T7945
Synonym:
Target: VEGFR, PDGFR, c-Kit
Ningetinib Tosylate
TQ0041
Synonym:
Target: VEGFR, c-Met/HGFR, TAM Receptor
SAR131675
T6012
Synonym: SAR 131675
Target: VEGFR
Lucitanib
T15185
Synonym: E-3810
Target: VEGFR, FGFR
Nintedanib
T1777
Synonym: BIBF 1120,Intedanib
Target: VEGFR, FGFR, FLT, PDGFR, Src
SU5205
T3566
Synonym: SU 5205
Target: VEGFR
BMS-794833
T2419
Synonym:
Target: VEGFR, c-Met/HGFR
Ramucirumab
T9929
Synonym:
Target: VEGFR
PP121
T2415
Synonym:
Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck
ODM-203
T7611
Synonym:
Target: VEGFR, FGFR
Pazopanib
T0097L
Synonym: GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Telatinib
T6166
Synonym: Bay 57-9352
Target: VEGFR, PDGFR, c-Kit
R1530
TQ0317
Synonym: R-1530,R 1530
Target: VEGFR, FGFR, FLT, PDGFR
GW806742X
T11520
Synonym:
Target: MLK, VEGFR
Lenvatinib
T0520
Synonym: E7080
Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit
JI-101
T3476
Synonym: CGI-1842,JI 101
Target: VEGFR, PDGFR, Ephrin Receptor
ENMD-2076
T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
SU4312
T3570
Synonym: SU 4312,NSC 86429
Target: VEGFR, PDGFR
Axitinib
T1452
Synonym: AG-013736
Target: VEGFR, PDGFR, c-Kit
hVEGF-IN-1
T4288
Synonym:
Target: VEGFR
Semaxinib
T2064
Synonym: SU5416
Target: VEGFR
Ranibizumab
T9928
Synonym:
Target: VEGFR
EOC317
T4318
Synonym: ACTB-1003,ACTB1003,ACTB 1003
Target: VEGFR, FGFR, Tie-2
Gandotinib
T2638
Synonym: LY2784544
Target: VEGFR, FGFR, FLT, JAK
Toceranib
T13178
Synonym: PHA 291639E,SU11654
Target: VEGFR, PDGFR, c-Kit
Cediranib
T2500
Synonym: AZD2171,NSC-732208
Target: VEGFR, FLT, PDGFR, c-Kit, Autophagy
Ponatinib
T2372
Synonym: AP24534
Target: VEGFR, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Autophagy
(Rac)-SAR131675
T3691
Synonym: SAR131675
Target: VEGFR
Brivanib
T6036
Synonym: BMS-540215
Target: EGFR, VEGFR, FGFR, Autophagy
Vandetanib
T1656
Synonym: ZD6474
Target: Apoptosis, EGFR, VEGFR, Autophagy
Fruquintinib
T2656
Synonym: HMPL-013
Target: VEGFR
AZD2932
T1836
Synonym:
Target: VEGFR, FLT, PDGFR, c-Kit
Regorafenib monohydrate
T1792L
Synonym:
Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy
WHI-P180
T2032
Synonym: Janex 3
Target: EGFR, VEGFR, c-RET, CDK
Ilorasertib
TQ0059
Synonym: ABT-348
Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase
Regorafenib Hydrochloride
T8402
Synonym: BAY73-4506 hydrochloride
Target: Raf, VEGFR, c-RET, PDGFR, Autophagy
Lenvatinib mesylate
T8541
Synonym: E7080 (mesylate)
Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit
Orantinib
T6184
Synonym: SU6668,TSU-68,NSC 702827
Target: Apoptosis, VEGFR, FGFR, PDGFR
AAL-993
T21593
Synonym:
Target: VEGFR
1 2 3
カタログ番号 製品名 別名 ターゲット
T8213 Isolinderalactone NOS , STAT
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
T4A2456 Gamabufotalin Gamabufagin COX
1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.
T17280 (Z)-Guggulsterone Apoptosis , VEGFR , Akt
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
T2906 Tanshinone IIA Tanshinone B,Dan Shen ketone VEGFR
Tanshinone IIA (Tanshinone B)(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.
T3S0153 Xanthatin Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T3673 Mollugin Rubimaillin HER , JAK
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...
T7203 Oglufanide L-Glutamyl-L-tryptophan,H-Glu-Trp-OH VEGFR , HCV Protease , Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
T1152 Albendazole SKF-62979 HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
TN2019 Orobol 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon BCL , Caspase , PI3K
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit...
T1205 Chloramphenicol Chlornitromycin,Levomycetin,Chloromycetin ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
T13108 Pamufetinib H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115 VEGFR , c-Met/HGFR
Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase(IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively).
TWA2417 Sodium taurocholate Taurocholate Sodium Others
Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...
T14055 5Z-7-Oxozeaenol FR148083,L783279,LL-Z 1640-2 VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...
T38250 L-Sepiapterin
L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrat...
TN5050 Sprengerinin C NADPH-oxidase , VEGFR , p38 MAPK , ROS , Akt , PI3K , mTOR , p53
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Human Human Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPJ-00414 VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated Human Human Cells
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPJ-00593 VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His) Human Human Cells
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02474 ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-04168 ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00637 FLT1 Protein, Human, Recombinant (aa 1-328, His) Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-04645 TL1A Protein, Human, Recombinant (hFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-01168 ALK-1 Protein, Human, Recombinant (His) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-01321 DLL4 Protein, Human, Recombinant (His) Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) Human HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00356 Neuropilin-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-05740 Neuropilin-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-02367 Neuropilin-1 Protein, Human, Recombinant (isoform b, His) Human HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00776 DLL4 Protein, Human, Recombinant (hFc) Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-01337 DLL4 Protein, Mouse, Recombinant (His) Mouse HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-04803 DLL4 Protein, Human, Recombinant Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-05094 Tissue Factor Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost...
TMPY-02530 Tissue Factor Protein, Human, Recombinant (His) Human HEK293
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost...
TMPY-01059 BMPR2 Protein, Human, Recombinant (His) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-05053 ANGPTL2 Protein, Human, Recombinant (His) Human HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-05360 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (mFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-06613 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-05259 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His), Biotinylated Human CHO
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-04188 ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (hFc) Cynomolgus,Rhesus HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00083 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00212 ANGPT2/Angiopoietin-2 Protein, Canine, Recombinant (His) Canine HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-05733 FLT1 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPK-00988 ECSCR Protein, Mouse, Recombinant (hFc) Mouse HEK293
Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angio...
TMPK-00978 ECSCR Protein, Human, Recombinant (hFc) Human HEK293
Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angio...
TMPK-00645 VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His) Rhesus macaque HEK293
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migratio...
TMPK-00454 VEGFR2/KDR Protein, Human, Recombinant (His & Avi) Human HEK293
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migratio...
TMPY-06620 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-06780 FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-01937 VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01069 VEGFR3/FLT4 Protein, Human, Recombinant (hFc) Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-03299 FLT1 Protein, Rat, Recombinant (His) Rat HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-02108 FLT1 Protein, Human, Recombinant (aa 1-756, His) Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-00119 FLT1 Protein, Human, Recombinant (hFc) Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-06665 FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-00662 ALK-1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPK-00451 VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTKs).yrosine-...
TMPY-05802 TL1A Protein, Human, Recombinant (His) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-04978 TL1A Protein, Human, Recombinant (rFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-04979 TL1A Protein, Human, Recombinant (mFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-03678 ALK-1 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
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VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
TMPJ-00412
Species: Human
Expression System: Human Cells
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated
TMPJ-00414
Species: Human
Expression System: Human Cells
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)
TMPJ-00593
Species: Human
Expression System: Human Cells
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)
TMPY-02474
Species: Mouse
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-04168
Species: Cynomolgus,Rhesus
Expression System: HEK293
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
Species: Human
Expression System: HEK293
FLT1 Protein, Human, Recombinant (aa 1-328, His)
TMPY-00637
Species: Human
Expression System: HEK293
TL1A Protein, Human, Recombinant (hFc)
TMPY-04645
Species: Human
Expression System: HEK293
ALK-1 Protein, Human, Recombinant (His)
TMPY-01168
Species: Human
Expression System: HEK293
DLL4 Protein, Human, Recombinant (His)
TMPY-01321
Species: Human
Expression System: HEK293
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
TMPY-00891
Species: Human
Expression System: HEK293
Neuropilin-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00356
Species: Cynomolgus
Expression System: HEK293
Neuropilin-1 Protein, Mouse, Recombinant (His)
TMPY-05740
Species: Mouse
Expression System: HEK293
Neuropilin-1 Protein, Human, Recombinant (isoform b, His)
TMPY-02367
Species: Human
Expression System: HEK293
DLL4 Protein, Human, Recombinant (hFc)
TMPY-00776
Species: Human
Expression System: HEK293
DLL4 Protein, Mouse, Recombinant (His)
TMPY-01337
Species: Mouse
Expression System: HEK293
DLL4 Protein, Human, Recombinant
TMPY-04803
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (hFc)
TMPY-03763
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (His)
TMPY-00892
Species: Human
Expression System: HEK293
Tissue Factor Protein, Cynomolgus, Recombinant (His)
TMPY-05094
Species: Cynomolgus
Expression System: HEK293
Tissue Factor Protein, Human, Recombinant (His)
TMPY-02530
Species: Human
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His)
TMPY-01059
Species: Human
Expression System: HEK293
ANGPTL2 Protein, Human, Recombinant (His)
TMPY-05053
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (mFc)
TMPY-05360
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06613
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His), Biotinylated
TMPY-05259
Species: Human
Expression System: CHO
ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
TMPY-04188
Species: Cynomolgus,Rhesus
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His)
TMPY-00083
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Canine, Recombinant (His)
TMPY-00212
Species: Canine
Expression System: HEK293
FLT1 Protein, Mouse, Recombinant (His)
TMPY-05733
Species: Mouse
Expression System: HEK293
ECSCR Protein, Mouse, Recombinant (hFc)
TMPK-00988
Species: Mouse
Expression System: HEK293
ECSCR Protein, Human, Recombinant (hFc)
TMPK-00978
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
TMPK-00645
Species: Rhesus macaque
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His & Avi)
TMPK-00454
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06620
Species: Human
Expression System: HEK293
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06780
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
TMPY-01937
Species: Mouse
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
TMPY-01069
Species: Human
Expression System: HEK293
FLT1 Protein, Rat, Recombinant (His)
TMPY-03299
Species: Rat
Expression System: HEK293
FLT1 Protein, Human, Recombinant (aa 1-756, His)
TMPY-02108
Species: Human
Expression System: HEK293
FLT1 Protein, Human, Recombinant (hFc)
TMPY-00119
Species: Human
Expression System: HEK293
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06665
Species: Mouse
Expression System: HEK293
ALK-1 Protein, Mouse, Recombinant (His & hFc)
TMPY-00662
Species: Mouse
Expression System: HEK293
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00451
Species: Human
Expression System: HEK293
TL1A Protein, Human, Recombinant (His)
TMPY-05802
Species: Human
Expression System: HEK293
TL1A Protein, Human, Recombinant (rFc)
TMPY-04978
Species: Human
Expression System: HEK293
TL1A Protein, Human, Recombinant (mFc)
TMPY-04979
Species: Human
Expression System: HEK293
ALK-1 Protein, Canine, Recombinant (hFc)
TMPY-03678
Species: Canine
Expression System: HEK293
カタログ番号 製品名
L2193 Anti-Liver Cancer Compound Library

1816 compounds
1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.